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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6c21d9732705aec810a939c385bd1d9bbd2e4aca43658388c0cc773d8579582' 
  AND token = 'bSOd+FBCv1uDWeVu7BENbfP+ShVcFh1T/qX3QbtQX/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}