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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '900957d38ba5743a7b9ecd90e24c5dffcccc255ff4ba82388f1a20c7bb456a31' 
  AND token = 'vPO2HmcvVSz8Pqzu//jr6Zia6ep61Gxm0jv4r7KyzHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}