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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5986efeef9dc7aed09234fb421e15e53577a3e2f05fe541054962ffcf70b5051' 
  AND token = 'l3JsBXGInyhIKZTo0cXf7/XQOg7gdMfOLM8CaxuArUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}