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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edefbf79caa5856599cf74ab5be4ca4e259af5a951e5cebd7b464196f08a0699' 
  AND token = 'wghUXQS4RQjbdwy+xLfAOQO6geTRB+GRfFyVkVhe7tU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}