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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a24b9e0efcfc36c524bed9fa1dcb7e5a946ba0087be8483411d0501f08448a7' 
  AND token = '3VwbkI5tjtgnYY4B6zYeYJBYMRFLmiixy/nZW4WLsmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}