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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c174c00c92a8882b02bedfe07a5cf41b9c78abc01a212c7e215f1ee0c051dd32' 
  AND token = 'BJep8v/a84gQzBQWJtgtDO6yTSqmJmXGvxMPyYzGxcc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}