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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a968aa2e6af59552f20a1a6133d75bdc0ff0414f5b3cbc31a8495cc9612f557a' 
  AND token = '6gcQRWMsRynRdkF/aLAvN4fjJAEmfBEXKI637gXm/Tc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}