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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '368847e4b3110cd8f2a53f9ca4657e566f930e6af64d1fc9d3d64e910efa5df7' 
  AND token = 'QQvwsjeSmcqfMIY/cxcV9Kg77AHp0Nn3cmYbxyc7tI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}