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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd77cd65cb44e7f553cda13c29402e69b1febec6efac33af3b96d189098c4bc2f' 
  AND token = 'GTE9CIoitWyTwZZ+wXEG+qdIlK+a1UVVwu6QRKtcUDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}