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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e65c71c94fb06c58e46aee14c19ad1e9e1800f3f8730d93472413e52c893127f' 
  AND token = 'uWaCB3VYQbSj/s/5xxqSC1FHP8cSaO5WahUGEDrmAE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}