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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c9b923761678427f361d63a3643f90d80cad7d1c70276cbb40613bd88ca5be8' 
  AND token = 'FAQQDHO7geIcuGtYOiL1QfgqLhMp5+hh7S5UEJ8OC0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}