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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1cc1e68bb2711c7e40fff5b6b46b8378cbfbefb10643cdf5f0ba87237186e1e' 
  AND token = 'Da2CY4aNqJh+yicqN9Ms2JwgUVV835zgjWBq0dBdMz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}