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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f2c986365857bab41ca99bf2f5d525b646dd64f4ed490ec00f5220ccf4f8173' 
  AND token = 'uPdesKd+QnTCb7pOBX+2G+txsJ4DHxib4D91tXMVzsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}