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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfa78a77b9f1f591c6874f3ff95514b95d24aa5eaf650f0cfb935244538fe5d5' 
  AND token = 'W/S71vSOmN+pYs5MFXpAyj7OwxwXiXlyJ4V700GdRVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}