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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8e02681d047bf3d264e1d81b0fb23c76fb4aaebae8a46fe3903cf429f823007' 
  AND token = 'Iddr1jy9eJQr1T3Gda8YjcFCjzrJ0lVHr6jesdWCTjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}