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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb4990f6a6e6002924d9314f8a77e68f7fb69fe461243f2a2bd8b95e18415b40' 
  AND token = 'pkE6b9m+53Yc6WOpfJgDVNJWXlum+kAY7CjlSysiplI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}