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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c29256019f5617801efd5823109b1e60fbbc0705bc5e15425c2d283d6bd7f08' 
  AND token = 'zCnt493twpJEtRwGRpXCyHjo9++E007Y6l/TLt5p3gg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}