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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55d3024313e8c005c6fc91ba644c8986fa3cdfd06cb403acbc01e65ca3dbc987' 
  AND token = 'm4EAfNJA4GXlB8I5qJ31G1iWm/ud4bWSF3wogq1RzYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}