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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67145f50cbe110a83c390b138bfa78994714e60f735e7a0a9b4a2875f516c2b4' 
  AND token = 'D4uzpcWy/PdjH6lfR9ibgB+TnX5ELpLwaF0T/ADFx3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}