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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fe7ada01b549329e42a03bc19155d011d8630ed98f9c4ff40e035dcbf68befc' 
  AND token = 'PKs3lF5LKheV+8XJUEeMtGNDv6x4yDLbuPDv4W4eACw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}