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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8129da71902f3e9e240d76ab88bf0fecd5a19e81be88c5e909f74b6bf11388b' 
  AND token = 'K778kwQdkKw+GupoMUV0EmyAi3VciLa5sUkwcVFuBQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}