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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8c3851a4e82d84a1bf617469699b661afc9a81bdd6248a0e08acaa5004d29d6' 
  AND token = 'Ij3ITxbQmw6kgpuCCSRynh9NoSwhVRvCYZUCAHr/ImM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}