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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38eff3a9b6604494f78b5c9cb1bb82b0885616f8054048a3de178afa180e1cfc' 
  AND token = 'ImqSH3l8UmRQnTRZETT6LaIdl+n3EobzF+fcnGNU2DE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}