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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7220a83c93802a71465e812ebbd3121d14400620d42cc71a971cdbc61a2f7fed' 
  AND token = 'ku26Af4AxOs3Yq8qyCihdZhjUjx8G+x7qj7t4MmUUV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}