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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a87fa219255541514c81102274c66d633f208d4a0719f385c4bb50ee85701ba' 
  AND token = 'r1ZJVPTEMcaCJI9AGjTtDsDWRrBXgI3BmQvA59OUmTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}