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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5627c34fa9f2d1a6b1205d4a32c05f670b6ee186fa12929a593b0eb34b1184b8' 
  AND token = 'UcNOE8Xza9a5cV7M4ZycwOCOI9B6VSHyokbx3Pwt754=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}