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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '538b8fce55fcdb926b5afabd2739313def8d7548d776260ae2d48311c248255a' 
  AND token = 'sDs3rCjCvXQp+SjsvKkF1Esr0xETHSGcovsVk9QU0Qw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}