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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d58560af170c0c9ad66e4ce10aa44ac6abaa106fe0e4993b93029ed4538ee37' 
  AND token = 'WvVh1FHSkD9YmROHJ4PWZIP++TbEtn0QIJq8ltSkDAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}