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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d959e005ae9ba1efe1ad01d126fff6507c4c09a82e59da07501ac530bd41fc9' 
  AND token = 'yKL4CjceMmZguEl8hkU3NXpxG7aR7LW1XxN0pZ9NfTU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}