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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12f6eff6add4e2498a05237043bff9d392a40e085548e903700011c9303effee' 
  AND token = 'rxLcUlTRDi45dx4rrNr1C2SzfVxncCZ0fbC+yh8qH0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}