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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76e160bd1cfa38fa4f5aefaeee6b4c023032536848fba23ee0fa3e735255e436' 
  AND token = '+o/uqFx60gEPNUEV0HRs5b49GsVsC9QG+cOFI1ouBWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}