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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9380643da4c69c9ac4261eb903291c7355921b3d4585b399419edd8374e147ef' 
  AND token = 'k+A8xASklvB4F09jD6HvM7ZxFonSrEnqDu1G4Yr73GI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}