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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'adc7ad27011c8e48de983f0fe226404f22e6b75ded574435abcdb0aec3481c6c' 
  AND token = 'JIsztrB9PalFwOkfRhEkPq73nSInZIGpl1Pe8yDzBSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}