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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28b302b97d5c4a53c09a272c25f66dcb9efbb93d4fafbaf59c9ff9474bf4a5f5' 
  AND token = 'IOAH3y+eqcsDOxPTNmD9tYeXPD1MA38wgTcFnCT2Jjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}