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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea21abbae21cb579e493fc343889b9ee049f07e404f269c3098651f48f02e6da' 
  AND token = 'h4OXEVXvt3ZkKs9JRpb62rq3GwvHYShyEpAnHTwDR5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}