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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05cd496215c2a0919670c37d4ca3f2880d6a09189162acaf05ae7960217d10ee' 
  AND token = '2XB1jb+O4gWjv2Mspdpb07Z3WE+SUlmFJlWj8fuwzcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}