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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d4a92afb4314007e36a0a6f3e520f8c4607bae64221ef92403dec85459a9b9c' 
  AND token = 'a3BUG+5pq8KdS+S8hy1408bq0eOdPjH9koHbQPu02oo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}