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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3781ae76063a6c3e55c4f60955913581b30798e399493fd232022856c1f92bbc' 
  AND token = '0DId9+4ShvJiRtArLtXE7O1eF/z2JvNRntFPzV7gLXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}