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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cc8b79af3e7cb261ea9009b806407a1e8964df32ff9d890726ee1265366b599' 
  AND token = 'qRjcVobspCl4mskTOZhTJObm+rYS2S1DfElvDoI6cik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}