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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00e1acdc1605694bd495c1c4c22e436f5c6f716b7dbe8b847192ecdfe5bdbfe8' 
  AND token = '0cgfPyp0n0ZNMc1s3e9i5q1EceMNu0tLmpfU6qAR0bM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}