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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca29a883e0530b853f5d50cdd07bd30e68404c66052934e02b174bbb36de5aec' 
  AND token = 'ZFlexYuinUccFIm3b1Qa4NHs7dRncRatWQFuX9J8EAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}