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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41291bcb0832db0346ea7a1558ba771f7467e562c7eb905482a85d0666dd690a' 
  AND token = 'AxXpHDeyx9hrRX1jG/uBX8A9d4Fv91i53ETUXhUReeA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}