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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cffd6c8f577cc648f1f1b72648cf4474cc6ae73b07b52ab70e1dbea714bae60f' 
  AND token = '5Tm2TnXXqbv0UaTg9vBHU8dk85Z5qQUjQuqpDoO4XyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}