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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e245d7cdc9b75d7833dbaedb55815145a0bc15d90134fe2e2093be19114ae6c1' 
  AND token = 'wmRqSYF5p1qeG9gEqXEkFAcGFDu379mAqCJM9mG6Vw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}