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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1991b1f5b779af8814b5f6c3b6e0fe8f9f422fdcd73e0a0c49ece2b01281fad0' 
  AND token = 'I+S1YcQwScIXsYpB5mkQuNTk1vGq7h5xGttXmhchpVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}