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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf580363a6d26a284ab4757dafd9dbcc8ee87581c637343dff519b2fefbfe1f1' 
  AND token = '8aMG2lRfu5jVQjcL8A78EuZ3Zabpvmyg+ifbSA7W1MI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}