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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c37a1f5b93f9fd693534e696dd4487ccf5fef117d72c2ffd01e724f8055469d2' 
  AND token = 'yjw0yGQdsGYqlt2zyEWo6rXrGRPbixkZ/SopCZ5GBMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}