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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7861404266c3a20544e306c82ac854ef9d7cac5ef9ff29ba2f4fb8b2881a56b6' 
  AND token = 'gEBPpsGZ3mgYkr/TyEgNz1GbSAnMkdUGv40XI/FDzbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}