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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1adf76290be3eb2d17b089f4ff94fd53ff88a900a3013c7ba56b7f469c003e07' 
  AND token = 'A7iLNKPjkqXItZXIvFp6rVFPx8yGxfsyn5v3RWjdFq4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}