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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68a8e57b1fbcf278033e2d17f1dbc7ae32391fd3afad6a9610fd04184520c818' 
  AND token = 'V9UsAGncCnScuImfrhwKrIqPDsDpdJVCYGDR2dewE1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}